Yes, if the wire is old and frayed or if it is rubbing against metal the wire could ground out and discharge into the engine block before it get to the spark plug causing the plug to misfire. If the contacts are worn or loose you could also get an intermittent misfire.
Were the spark plug wires replaced? Even a pinhole in a plug wire can leak enough spark to cause a misfire. Try swapping that wire with another similar length wire from another plug and see where the misfire is then. If the misfire moves to the new cylinder or ceases completely, you'll know the wire was bad.
Spark plug, plug wire, distributor cap, injector, internal engineSpark plug, plug wire, distributor cap, injector, internal engine
bad spark plugs or bad wire connection to the spark plug
It could just be a bad spark plug wire or the spark plugs need changing.
Bad spark plug or plug wire or one or both valves leaking or stuck. Time for a compression check or spark check.
bad spark plug wire.
Spark plug, plug wire, distributor cap, injector, internal engine ........as in a blown head gasket.
Bad spark plug, plug wire. I hade that problem it was a cracked head "Expensive"
p0302: cylinder number 2 misfire. Spark plug, wire, injector, internal engine,
A cylinder misfire could be from a bad spark plug, bad spark plug wire, or a bad coil. It could also be caused by a plugged or faulty fuel injector.
That is usually electrical. Depending in the vehicle, a spark plug wire, a spark plug, or a coil, if individual coil.
It can be the spark plug or the plug wire. In some cases it could be a vacuum leak.