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Yes, there are many Migraine medications that can cause this symptom.

For best results, seek out the help of a Migraine and Headache Specialist. These doctors are specially trained in the diagnosis and treatment of headache disorders beyond the scope of neurologists and primary care doctors. ______________________________________________

It depends which medication.

They are finding out that Topamax and Zonegran (both anti-epileptic medications used for migraine prevention) may decrease potassium in the body. Low potassium can cause muscle cramps.

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Q: Can migraine medication cause leg cramping?
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