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They can, but combining the 2 defeats the purpose of each drug's usage.

Tramadol (Ultram) is a relatively moderate painkiller that is prescribed when stronger meds aren't indicated, or there is a risk to the patient of the side effects of opiates (morphine intolerance, etc.).

Oxycodone is a Schedule II opiate, and as such has many side effects that Tramadol doesn't.

If your primary prescription if for Oxycodone and you add Tramadol, you probably won't feel much, if any, additional pain relief as Sched II drugs are the strongest available by prescription.

If your prescription if for Tramadol and you add Oxycodone, then you're effectively bypassing all of the reasons that Tramadol was prescribed to begin with - because it doesn't have the side effects of opiates.

If you're taking Tramadol but are having pain it's not taking care of and you feel you need something stronger, the first thing you want to do is to start a Pain Diary. You can get one at Painfoundation.org. Most doctors are reluctant to prescribe Schedule III or II drugs because of the possibility of abuse, which is stupid considering that 95% of people who have a legitimate medical need for stronger pain meds don't abuse them.

By documenting your pain, you can show evidence over time that your pain is real and has a pattern that your pain meds aren't helping. Real pain is very hard to fake, as is a Pain Diary. Most people might think it's easy to fool a doctor, but people who have either experienced pain or dealt with people in extreme pain know when they're being BS'd. By having written, documented evidence of your pain history, your doctor can't just say that your pain is in your head or that you have no need for stronger medication. If you do have evidence and your doctor refuses to help, then it's time to find another doctor. Contrary to what we're brought up to believe, doctors are not all knowing - they're humans who make mistakes that can cost someone their life. The difference between them and us is that when they make a mistake and someone dies, nothing happens since they're doctors and medicine isn't an "exact science". If we kill someone our lives end by going to jail. Doctors regulating doctors is as stupid as believing that politicians can be trusted with a piggybank.

While it might take time to document your pain, in the end it's worth it. One, it shows that you have a real problem, and two, that you're serious in taking control of your health care. Three, if someone labels you a "drug seeker" for asking for stronger meds, you have something to shove back in their faces.

( I totally agree with everything you say expecially the pain diary and drs who label you as a drug seeker simply cause the meds they think should help you are not they automatically jump to the conclusuion that your an addict and are a so called "drug seeker" and its a shame there are dr's like that out there.. and theres alot out there.. its a terrible shame.. On the other hand Tramadol is for neuropathic pain like for nerve pain as well as a narcotic pain reliever. I've used it in combo with percocet for my nerve pain and it helped with the nerve pain from my hurniated disc.alone no tramadol has nothing comparable to percocet for pain but for the nerve pain yes it helps. its kinda like a lyrica or neurotion type med also..

I would like to add a couple things. First about taking Percocet and Ultram together.

If you're pain is mild to moderate, I would recommend the Ultram first. If there is no change and the pain persist after four to six hours, I would recommend taking the Percocet. I highly advise not taking them in conjuntion. Most doctors I have went to have always advised me to take one or the other four to six hours apart. Choosing which one to take first depends on how bad your pain is.

The other thing I would like to add is in reference to the comments about drug seeking. I won't comment about my personal medical conditions, however, I will say that my conditions warrant taking narcotic pain relievers. I can't begin to tell you how many times I went into various doctors offices looking for not only pain killers but a Doctor Who was willing to help with the actual problem. Each time I was labeled a drug seeker. I would tell the doctor exactly what was wrong with me and ask for Lortab or Percocet and then come out with a prescription for some stupid ibuprofen.

Not only was that a waste of my time, it was a waste of a hundred dollars just to see that doctor: only to be given something I did not need. So as the person above mentioned a "pain diary", that is exactly what I started. Over the course of a month I started a journal and I also had to go to the emergency room four different times for the same thing. I ended up getting a CT Scan and an MRI and come to find out I had some serious problems. I went back to the hospital and got my medical records of everything the ER doctors had done for me and what the diagnosis was. I made an appointment to see a new doctor but ONLY for a consultation. I found this was a good method because it served two purposes. I was able to consult with the doctor about my problems with proof in hand and ask if he could help with narcotic pain medication and I didn't have to pay a doctors visit fee and be out a hundred bucks to get a whole lotta nothing. I also signed an authorization to release my records from the ER I went to so the doctor could see for himself just in case he may have assumed that I brought fake documentation. The point is: Doctors have a bad tendency to judge people and label them addicts and drug seekers when patients ask for narcotics. They have an arsenal of worthless drugs opposite of what you need as well as excuses as to why they will not prescribe them. When they start that, remind them that you are there for a legitimate problem and not there to be judged because of other people who have abused narcotics or to have your time and money wasted. Then get up and walk out and go somewhere else. Eventually you will find a doctor who will help you.

Just remember: take your medicine as prescribed. It's hard enough to find a doctor who will prescribe narcotics these days. Don't do anything to get cut off.

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14y ago
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15y ago

As long as you keep the doses reasonable, I would not assume this would cause any adverse reactions, since mixing opiates is not known to cause any negative effects. However if you are using recreationally, tramadol is really a terrible choice considering it can cause sleeplessness and convulsions at high doses. For recreational use you would be better off just taking oxycodone.

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10y ago

You should not exceed more than 650-1,000 mg of acetaminophen within 4 hours. Previous FDA guideline was that you may not exceed 6,000 mg in a day. In 2011, it changed to 3,900 mg in a day. As for mixing Hydrocodone (the opiate in Vicodin) and Oxycodone (the opiate in Percocet) only do so with doctor's recommendation, and wait at least 4 hours after taking Vicodin/Hydrocodone or Percocet/Oxycodone before taking the other medication.

If you do not have pain or do not have a prescription please seek medical help immediately, as these medications are highly addictive, and if used improperly can cause death.

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14y ago

No, oxycodone contains chemicals found in oxycotton and tylenol. It is not smart to mix Advil and oxycodone because it would mean mixing the two generic pain relievers.

Just because the hospital's open 24/7 don't mean a thing, keep your self alive do not over drug you'r self. Next time you'r wondering please don't ask for online help go call you're local pharmacy they could really help.

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11y ago

for me, I take 25mg tramadol in morn. and at night, then I take my percocet 5/325 every 4 hours. Sure makes life a little moe tolerable!

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Q: Can oxycodone and tramadol be taken together?
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