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Hell no. .410 is not a gauge it is a caliber. True gauge is a measurement of the number of lead balls of bore diameter that constitute a pound. The .243 bullet is a lot smaller than the diameter of a .410 barrel. There are some .410's that can shoot 45 colts but not all can.

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14y ago
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Q: Can you safely shoot a 243 caliber bullet from a 410 gauge?
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