Can you take depakote and Ativan together?

Answer 1

Although this combination of medications are used routinely in various patients, it should first be noted that Ativan ( as well as all other benzodiazepines) is HIGHLY ADDICTIVE and there are alternatives for treating anxiety that can be used instead of Ativan (Various SSRI's also treat anxiety without the possibility of addiction. I.e. Prozac, Zoloft, etc...). The coocurrence of addiction in those with BiPolar Mood Disoder and the various Anxiety Disorders IS high and therefor, consideration for "switching" addictions from alcohol or other substances to the benzodiazepine of choice should be discussed in detail with your physician! Specifically, in regard to the question as posted, Depakote CAN inhibit the metabolism of Ativan which - in turn - could lead to higher levels of Ativan (other than that intended) in the bloodstream. Being that blood levels of Depakote should be monitored with regularity by the prescriber whenever prescribed, blood levels of Ativan will likely be a focus as well. If you are taking a benzodiazepine (Ativan, Valium, Xanax, Klonopin, etc..) for ANY reason, sinceity and honesty with your physician - in regard to your substance use/abuse - is paramount! BSalai - LCSW