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No, they only will work on the exact type(s) of flu that the vaccine is made to prevent. In the US, the seasonal flu vaccine contains the antigen for three different types of flu each year that are chosen as the mostly likely to be spreading during that season. If there are very similar strains circulating, the vaccine can sometimes provide some carry over protection to the similar ones, but you can only count on protection from the exact types included in the vaccines.

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