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Yes, they both do. Its purpose is to oxidize small foreign organic molecules (xenobiotics), such as toxins or drugs, so that they can be removed from the body.

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Q: Do men and women have the liver enzyme CYP3A4?
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Do men have an enzyme in their stomach that breaks down alcohol?

Enzymes in the stomach act to break down a proportion of the alcohol taken in by a person. However most of the alcohol is broken down in the liver. However, these enzymes are less active in women than in men.


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Indirectly. Blood alcohol content (BAC) is always dependent on how much you drink. However, women do not produce as much of the enzyme that metabolizes alcohol in the liver. That means that their BAC will become higher and remain high longer than a male for a given amount of drinking, as the liver will not be able to remove it as efficiently.This also means that women who drink heavily tend to develop advanced alcoholism sooner than men, and die sooner if they continue to drink.


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Women are generally smaller than men, and they produce less of the enzyme that breaks down alcohol. For those reasons, most women will have a higher BAC than the average male if they both drink the same amount of alcohol.


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Why are women's livers larger than men's?

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Why do men with cirrhosis of the liver develop gynecomastia?

Men with cirrhosis of the liver will often develop gynecomastia from increased production of estrogens.


How do men eliminate alcohol faster than women?

Men generally have more muscle mass and higher levels of the enzyme alcohol dehydrogenase, which helps break down alcohol in the body. As a result, men tend to metabolize alcohol faster and eliminate it from their system more quickly than women.