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Yes there is a connection , those who suffer from sickle cell anemia, nicotine makes it a worse condition.

nicotine cause blood vessels to contract more which cause increased pain, and causes reduced oxygen to the lungs.

Those with sickle cell is anemic and nicotine further deletes the supply of oxygen to the body.

I know a person who did not wanted to quit smoking and he had sickle cell diseases. He was taking medication but it did not help because of nicotine, so he passed away earlier than expected.

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11y ago
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Q: Do nicotine and sickle cell disease have any connections?
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