First you must post a question that makes sense!!
The lock cylinder is most likely bad. Otherwise if you're trying to remove the key from the car make sure it is fully in park.
Toyota Avalon
On my 95 Avalon, there was a yellow picture of a car showing that my rear lights (license plate) were out.
Yes. after a period of time either the chip will "forget" of the "reader" can go bad. Sometimes if you turn the key to "run" position without trying to start the car for about 2 minutes key may "reprogram" itself.
Using the master key.
change battery in a 2007 toyota avalion key fob
The Avalon is listed under Full-Size Luxury Sedan.
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Insert your key into the door lock and turn.
either have the beeper fixed or have the car rewired to shut everything down once the key is removed.
Your ignition key wil open it.
Take the vin number from the windshield to any Toyota dealer and they should be able to make a key from it for you. This can be expensive depending on the type of key you want. They can just make that will get you in the door though.