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How can a mutation in a DNA base sequence cause a change in a proteins?
Wiki User
∙ 9y ago
dna in a cell needs protein and chromosomes.
Lottie Von
Wiki User
∙ 13y agoA change as small as one base pair in a codon can have profound consequences on the function of the affected organism.
Suppose a cosmic ray or an ultraviolet ray brushes by a segment of DNA that codes for the RNA sequence UUU (meaning three uracil nucleotides in a row), and changes just one of those nucleotides into a different one. The RNA sequence UUU codes for the amino acid phenylalanine. Suppose the DNA was changed so that just one of these nucleotides was changed. In the case that the RNA codon was changed to UUC (meaning the last uracil in sequence was changed to a cytosine), then nothing would happen, for UUC also codes for phenylalanine. But if the DNA were changed so that the final uracil were replaced with a guanine or an adenosine (UUG or UUA), then the RNA would now code for the amino acid leucine.
This doesn't sound like a big difference, but amino acids are the building blocks of proteins, which are the building blocks of the body, and changing only one of them can make a major change in bodily structure and function. For example, although hemoglobin is a large and complex protein built out of hundreds of amino acids, the hemoglobin of people with sickle-cell anemia differs from that of normal people by only a few amino acids.
Wiki User
∙ 8y agoThe DNA code is 'read' in threes. Each group of threes equals one amino acid. Proteins are made of chains of amino acids much like a sentence is a string of three letter words. If one of the three is not what it should be (a mutation or mistake), then the amino acid will make no sense.
Some mutations can make sense but many don't.
Mutations that replaces one base for another will result in something like this: The beg red peg ate the red rag. (The big red pig ate the red rag is correct). This mutation can be read OK.
But another type might make the sentence totally unreadable: The big res dpi gat eth ere dra g.
Wiki User
∙ 13y agoSome mutations produce new traits that can help an organism survive.
Wiki User
∙ 12y agoI'll have your answer tomorrow
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Which do you suppose would be more harmful A mutation that changed the nucleotide sequence of an mRNA molecule or a mutation that changed the nucleotide sequence of a DNA molecule?
A mutation in a DNA nucleotide sequence would be more harmful than a mutation in a mRNA nucleotide sequence because it could cause the synthesis of multiple nonfunctional proteins in comparison to a mutation in a mRNA nucleotide sequence that would be less harmful because it would result in a few nonfunctional proteins.
What is a permanent change in the DNA sequence of a gene?
Basically change in the DNA sequence of a gene is associated with change in the nucleotide sequence which may result in Mutation and may cause loss of function of that particular mutated gene.
How can a mutation in DNA base sequence cause a change in a protein?
dna in a cell needs protein and chromosomes.
How does an insertion sequence cause a mutation?
In the DNA, the sequence of nucleotides determines how proteins are built, with each segment of three nucleotides encoding a single amino acid. When one nucleotide is inserted into the sequence, the whole sequence shifts, and all the triples are changed completely, which can cause detrimental mutations.
What type of mutation is the most significant effect on protein synthesis?
Mutations change the order in which the organic bases are in your DNA. These bases code for proteins, and if they change, so the code changes. A change in the code can mean a different protein is made or that proteins are not made at all. The way it could stop proteins from being made is that the change could create a Stop Codon, which stops mRNA from being translated (which would then be transcribed into proteins). If it forms a Start Codon, then the wrong section of DNA could be translated and the wrong proteins be synthesised. There is not always a change in to proteins synthesised, as for each amino acid in a protein there is more than one code. A mutation could change the code for a protein into a different code, but for the same protein. In such a case there would be no change.
Which do you suppose would be more harmful A mutation that changed the nucleotide sequence of an mRNA molecule or a mutation that changed the nucleotide sequence of a DNA molecule?
A mutation in a DNA nucleotide sequence would be more harmful than a mutation in a mRNA nucleotide sequence because it could cause the synthesis of multiple nonfunctional proteins in comparison to a mutation in a mRNA nucleotide sequence that would be less harmful because it would result in a few nonfunctional proteins.
What makes proteins accurate?
The proteins are coded in DNA. So the gene expression cause RNA and proteins in solely depend on message in DNA. When there is accuracy in DNA (without any mutation), there will authentic proteins. If any change occurs in the DNA sequence that may form premature or dysfunctional proteins due to the change in amino acids.
In your own words write a definition for the word mutation?
mutation: a change in the sequence of DNA to cause a unusal trait
How can a mutation in a base sequence cause a change in a protein?
dna in a cell needs protein and chromosomes.
WhIch best describes the initial change cause by a DNA mutation?
a chnge in the sequence of base pairs
A change in the genetic material of a cell is called?
Cancer- certain mutations (changes) in a cell's genetic material may cause that cell to reproduce with out control.
What permanent change in the sequence of DNA in a gene is a?
Basically change in the DNA sequence of a gene is associated with change in the nucleotide sequence which may result in Mutation and may cause loss of function of that particular mutated gene.
What is a permanent change in the DNA sequence of a gene?
Basically change in the DNA sequence of a gene is associated with change in the nucleotide sequence which may result in Mutation and may cause loss of function of that particular mutated gene.
How can a mutation in a DNA bases sequence cause a change in a protein?
dna in a cell needs protein and chromosomes.
How can a mutation in a DNA base sequence cause change in a protein?
dna in a cell needs protein and chromosomes.
How can a mutation in DNA base sequence cause a change in a protein?
dna in a cell needs protein and chromosomes.
What effect does a mutation have on DNA and proteins?
It will change the order of bases:) could cause diseases such as; Cystic Fibrosis
