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Where can one find information about Cyclooxygenase?
Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to prostaglandins was first identified over 20 years ago. Drugs, like aspirin, that inhibit cyclooxygenase activity have been available to the public for about 100 years. In the past decade, however, more progress has been made in understanding the role of cyclooxygenase enzymes in biology and disease than at any other time in history. Two cyclooxygenase isoforms have been identified and are referred to as COX-1 and COX-2. Under many circumstances the COX-1 enzyme is produced constitutively (i.e., gastric mucosa) whereas COX-2 is inducible (i.e., sites of inflammation). Here, we summarize the current understanding of the role of cyclooxygenase-1 and -2 in different physiological situations and disease processes ranging from inflammation to cancer.
Do platelets have nucleus?
No, platelets are cell fragments. They do not have a nucleus.
What does Cyclooxygenase 1 do?
Cyclooxygenase 1 is important for homeostatic maintenance such as platelet aggregation, the regulation of blood flow in the kidney and stomach, and the regulation of gastric acid secretion
Which drugs blocks the cyclooxygenase pathway in platelets?
aspirin
What is the enzyme classification of cyclooxygenase?
oxidoreductase ,transferase ,hydrolases, lyases ,isomerases and ligases.
What are characteristics of inflammation?
The symptoms of inflammation are redness, swelling, heat, and pain, which are caused by increased blood flow into tissue. Inflammation is produce by local hormones, which are released by injured cells.These include prostaglandins that produce fever and the dilation of blood vessels associated with inflammation, and leukotrienes that attract certain white blood cells. These and other chemicals recruit immune cells to the site and promote healing of any damaged tissue.
Where is basophil produce?
basophils are white blood cells produced in the bone marrow and involved in inflammation
What can cause chronic inflammation?
Processes that can produce chronic inflammation are tuberculosis, inflammatory bowel diseases such as ulcerative colitis and Crohn's disease, silicosis, and the continued presence of a foreign body in a wound.
Is the body's immune response to allergens which are antigens that produce a hypersensitivity reaction including immediate inflammation?
Allergy
True-false chronic inflammation of the pericardium can produce a fibrotic coating over the heart that constricts the ventricles?
true
What role does cyclooxygenase play in pain and inflammation?
There are two types of Cox, theres Cox-1 and Cox-2. Cox-1 is an enzyme that helps regulate stomach acid and keep it in the stomach. While Cox-2 promotes inflammationin the body, now this is neccesarily a bad thing. Unless There becomes a high amount of Cox-2.
Can acne be made worse by stress?
inflammation! Yes it can. When you are stressed, it can cause your skin to produce more oil and you in effect to break out.
