aspirin
His use of drugs and alcohol led him on a pathway to depression.
Cox-2 inhibitors are non-steroidal anti-inflammatory drugs (NSAIDs) which selectively inhibit cyclooxygenase-2.
Antiplatelet drugs interact with platelets, which is a type of blood cell, to block platelets from aggregating into harmful clots.
Drugs act on the neurons in the limbic system.
Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to prostaglandins was first identified over 20 years ago. Drugs, like aspirin, that inhibit cyclooxygenase activity have been available to the public for about 100 years. In the past decade, however, more progress has been made in understanding the role of cyclooxygenase enzymes in biology and disease than at any other time in history. Two cyclooxygenase isoforms have been identified and are referred to as COX-1 and COX-2. Under many circumstances the COX-1 enzyme is produced constitutively (i.e., gastric mucosa) whereas COX-2 is inducible (i.e., sites of inflammation). Here, we summarize the current understanding of the role of cyclooxygenase-1 and -2 in different physiological situations and disease processes ranging from inflammation to cancer.
Motrin (ibuprofen) and other medications in the class of non-steroidal anti-inflammatory drugs (NSAIDs) affect platelet aggregation (decrease the ability of platelets to clump together and form clots). Therefore, Motrin can cause bleeding if you have low platelets or your platelets don't function properly.
Drugs act on the neurons in the reward pathway of the brain. Drugs increase the release of dopamine.
Anesthesia is the drug class that includes local, general, and nerve blocks.
An example of a drug that blocks release of a neurotransmitter is botulinum toxin (Ach) and atropine.
A psychoactive effect is an affect on mood or behavior caused by the misuse of drugs.
Mesolimbic Dopamine
Prolonged bleeding can be caused by problems with the platelets count or platelets function. Certain drugs can also cause prolonged bleeding such as blood thinners.