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Something I learned in my Biology class today:

The color alleles on cats are located on the X chromosomes in DNA. Calicos and tortoiseshell cats are usually female because they have an orange X chromosome and a black X chromosome. These two colors will be co-dominant, meaning that neither one or another will be prevalent on the cat's body. This is why calicos and tortoiseshell cats have random patterns of orange and black fur (the white fur, if any, is just a sort of background to the color).

Since two X chromosomes in an animal means that it is female and a XY sex chromosome layout means that the animal is male, it is extremely rare for a male cat to have both the orange and the black X chromosomes required for the calico coat. For this to be possible, the male cat must have a XXY layout of chromosomes - the equivalent of the human Klinefelter's Syndrome. This syndrome almost always leads to the sterility of the animal that has it, although there have supposedly been cases where individuals with Klinefelter's have been fertile. And as to why Klinefelter's causes sterility, I don't have a clue.

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14y ago
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Nikolaos Tziolas

Lvl 6
2y ago

Το ξέρουμε από το γεγονός ότι υπάρχει ένα σημάδι από κόψιμο πάνω στο αυτί.

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Wiki User

12y ago

Females are usually not, but male calico cats are almost always sterile.

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Wiki User

15y ago

no, they are not. --- Only male calico/tortoiseshell cats are sterile as a result of a rare genetic mutation.

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Wiki User

12y ago

if the male cat has three chromosomes (XXY).

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Wiki User

9y ago

There are a few ways to know a male cat is sterile. The best way to know is to ask a vet.

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Wiki User

10y ago

Something to do with their genes.

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Q: How do you know when a male cat is sterile?
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What is a sterile cat?

A sterile cat is one that cannot produce offspring. It can be a female that has been spayed or a male that has been neutered. It can also be from disease or a deformity.


Does anyone have a male calico cat?

The Calico cat is very likely to be female. It is a genetic trait that seems to be tied into the same genetics that govern their coat color.


What is the disability for male calico cat?

While the vast majority of calico cats are female, there is the occasional male. However, virtually all of these males are sterile. These cats are known as Kleinfelter males.


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