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Proteins are the polymers of amino acids and are digested by the proteases present in the gastric secretions and if the proteins are to be made available to the body in direct form orally, the small protein molecules can be used. The short chain protein molecule is to be covered by a covering which is resistant to the gastric secretions including dilute hydrochloric acid so that it comes out unaffected and reaches the small intestines where they are absorbed as such. The long chain protein molecules can not be used in this manner.

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Q: How do you make orally active protein pharmaceutical?
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How do you make orally active protein pharmaceutical. what is the major problem encountered?

By putting the proteins (eg--insulin) in a tablet whose coating is made of a material that does not get digest in stomachs acidic medium but dissolves in the intestines thus proteins get absorbed in intestine by villi


How do you make orally active proteins pharmaceutical. What is the major encountered?

By putting the proteins (eg--insulin) in a tablet whose coating is made of a material that does not get digest in stomachs acidic medium but dissolves in the intestines thus proteins get absorbed in intestine by villi


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