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How does an orally administered drug get from the GI tract to the brain?
Wiki User
∙ 13y ago
It gets into the blood which carries it to the brain.
Wiki User
∙ 13y ago
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What is a non parenteral drug?
A non-parenteral drug is one that is administered orally or by inhalation. Examples would be swallowing a pill or using an inhaler. Parenteral drugs are administered by injection or via transdermal patch (applied directly to the skin).
What kinds of drug need to be lipophilic?
Drugs which are administered percutaneously, sublingually, or have to cross the blood brain barrier have to be lipophilic.
Can bioavailability be more than 100 percent for orally administred drugs?
Basically no, due to two reasons:First, the drug is incompletely absorbed from the gastrointestinal tract, some of it exits the body unabsorbed along with the feces.Second, the absorbed amount of the drug undergoes first-pass metabolism; where the drug enters the hepatic portal system and is partly metabolized by the liver, thus, the amounts of drug reaching the systemic circulation unchanged is even less.Therefore, the bioavailability of orally administered drugs is always below a 100% and can never be a 100%.Moreover, its not logical for it to be more than 100%, since bioavailability by definition is the fraction of the amount of the drug administered that reaches the systemic circulation unchanged. It can't be more than 100% unless larger amounts of the drug reaches your circulation than the amount you already took orally, which is impossible.While it cannot be more than 100% for a single dose, if the drug is administered more often than the period necessary for complete elimination from the body, total serum concentration may be higher than 100% of the single dose. Such is the case with most antibiotics for example, which are administered at intervals of 4-6-12 hours to achieve and maintain plasma concentrations higher than the single dose. (PS I am not a health professional)
Can you plug vyvanse?
Yes. But plugging it doesn't make it anymore effective and/or stronger. The best route is orally so your GI tract can convert the majority of the drug into dextroamphetamine.
What is cefadroxil?
A drug that is administered orally and has a broad spectrum of antibiotic activity.For the source and more detailed information concerning this subject, click on the related links section (Answers.com) indicated below this answer box.
When someone is acidosis what hormone drug should be administered?
Insulin should be administered!!
What is the difference between a systemic effect and a local effect?
Systemic means that the drug acts in the whole body(usually drugs that are administered orally or i.v),having effect i various parts of the body(e.g:aspirin lowers fever AND thins blood AND eleviates pain AND can induce bleeding in the gastric tract).LOCAL means that the drug only acts in the area where it is administred(e.g:strepsils for a throatache,aciclovir oilment for herpes,etc) and is not absorbed into the bloodflow,therefor does not act in multiple levels of the body.
What is the most-commonly used drug in treating Parkinson's disease or Parkinsonian-like syndrome?
Levodopa (Larodopa) is the mainstay of Parkinson's treatment. The drug crosses the blood-brain barrier, and is converted to dopamine. The drug may be administered alone, or in combination with carbidopa (Lodosyn)
Why is it important for pharmacists in training to know the anatomy of the GIT?
It is important for pharmacists in training to know the anatomy of the gastrointestinal tract (GIT) because many medications are administered orally and undergo absorption, metabolism, and distribution within this system. Understanding the anatomy of the GIT helps pharmacists predict the site and rate of drug absorption, as well as identify potential drug-drug interactions or adverse side effects related to specific regions of the GIT. This knowledge is crucial for proper medication selection and counseling patients on optimal drug administration.
In what situations is parenteral administration used?
Parenteral administration is used when the patient is unable to take the drug orally, rapid action of medication is needed, and medication is ineffective in the gastrointestinal tract. Parenteral administration is also used to avoid the gastrointestinal tract and its first pass effect and to delivery medication to specific organs or tissues.
Which hormones can make a person susceptible to infection when administered for too long as a drug?
Glucocorticoids can make a person susceptible to infection when they are administered for too long as a drug.
How is the drug ice administered?
Needle oral and smking
