How does gender preference affect one's lifestyle?

That depends on your definitions of gender and lifestyle. You may be thinking of orientation and not gender preference. In the transgender world gender preference is what gender you wish to project and which one you prefer to be treated as. In this situation a difference in lifestyle (what you do with your time) may come from spending more time on your appearance, more time with counselors, more time contending with work issues related to your gender difference. If you are thinking of orientation (whether you like the same or the opposite sex) then no gender preference doesn't change lifestyle. Both homosexuals and heterosexuals have many different ways of living: quiet and unassuming, loud and in public. Being straight doesn't make you mousy, being gay doesn't make you loud.