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Streptomycin is a protein synthesis inhibitor. It binds to the S12 Protein of the 30S subunit of the bacterial ribosome, interfering with the binding of formyl-methionyl-tRNA to the 30S subunit. This prevents initiation of protein synthesis and leads to death of microbial cells. Humans have structurally different ribosomes from bacteria, thereby allowing the selectivity of this antibiotic for bacteria. However at low concentrations Streptomycin only inhibits growth of the bacteria by inducing prokaryotic ribosomes to misread mRNA. It is an antibiotic that inhibits both Gram-positive and Gram-negative bacteria and is a therefore a useful broad spectrum antibiotic
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Do bacteriostatic agents kill bacterial cells?
No
What are the compounds that kill bacterial cells without harming the cells of humans?
They are called antibiotics (meaning against life) and generally interfere in only a few specific chemical reactions, those found in bacterial cells but not human cells.
Bacterial smears are fixed before staining to?
affix the cells to the slide and to kill bacteria
What antibiotics are made with streptomyces griseus?
S. griseus produces antibiotic, streptomycin, and it is useful against gram negative bacteria. Streptomycin and its relatives are considered reserve antibiotics for resistant bacterial strands because they can be neurotoxic and nephrotoxic.
Does streptomycin kill gram negative bacteria?
It kills both gram negative and positive
Why bacterial cell are sensitive to streptomycin and chloramphenicol antibiotic?
The bacterial cells are sensitive to streptomycin and chloramphenicol antibiotic because it eliminates or reduces their binding to the cells.
Do bacteriostatic agents kill bacterial cells?
No
How can you kill bacterial cells by centrifugation?
Bacterial cells cannot be lysed (or killed) through centrifugation alone. Although repeated centrifugation and resuspending will kill many bacterial cells as a result of shear stress on the cell membrane
Why does streptomycin kill the bacteria and not us?
Streptomycin binds to bacterial 30S ribosomal subunit and inhibits protein production by the bacteria. Human beings are are not affected because our ribosomes have a 40S subunit and a 60S subunit, no 30S subunit.
What are the compounds that kill bacterial cells without harming the cells of humans?
They are called antibiotics (meaning against life) and generally interfere in only a few specific chemical reactions, those found in bacterial cells but not human cells.
Bacterial smears are fixed before staining to?
affix the cells to the slide and to kill bacteria
What antibiotics are made with streptomyces griseus?
S. griseus produces antibiotic, streptomycin, and it is useful against gram negative bacteria. Streptomycin and its relatives are considered reserve antibiotics for resistant bacterial strands because they can be neurotoxic and nephrotoxic.
Most antibiotics kill invading bacteria while minimally harming the host by?
targeting structures found only in bacterial cells and not the host cells
Bacterial cells do not have a genetic material?
no, bacterial cells do not have genetic material
Does streptomycin kill gram negative bacteria?
It kills both gram negative and positive
Do bacterial cells have a nuclues?
Bacterial cells are not eukaryotic cells, which means they do not have a nucleus. They do, however, have chromosome.
What has a prokaryotic cells?
Bacterial cells.
