A 3-base sequence of nitrogen bases on a molecule of mRNA is called a codon.
1. mRNA - provides 'template' for protein 2. tRNA - carries amino acids 3. microRNA/siRNA - regulate protein production
Certain small RNA molecules fold into loops. The Dicer enzyme cuts them into microRNA (miRNA). The strands then separate. An miRNA piece attaches to a cluster of proteins to form a silencing complex. The silencing complex binds to and destroys an mRNA molecule that contains a base sequence complementary to the miRNA. In this way, it blocks gene expression.
According to "Elementary Biochemistry" by J. Davies and B. Shaffer Littlewood, mRNA contains 100-5000 N-containing bases, which is also the # of nucleotides. I guess the size of the mRNA is related to the size of the protein molecule that is being synthesized. What is the largest protein made in the human body?
There are two mechanisms as related to above. Firstly, the removal of All Introns occurs - via the Spliceosome -, and then a "poly AAAAAAA" tail is attached to the [edited] mRna transcript just before its export to the cytoplasmic Ribosomes.
microRNA
A 3-base sequence of nitrogen bases on a molecule of mRNA is called a codon.
1. mRNA - provides 'template' for protein 2. tRNA - carries amino acids 3. microRNA/siRNA - regulate protein production
4 different RNAS exist. There is mRNA, tRNA, rRNA, and as of this past year microRNA. Although these are the only known ones there may be numerous more.
microRNA is a "non-coding RNA" molecule. This means that it does not translate into a protein. These are sometimes also called "non-messenger" RNA molecules.
Certain small RNA molecules fold into loops. The Dicer enzyme cuts them into microRNA (miRNA). The strands then separate. An miRNA piece attaches to a cluster of proteins to form a silencing complex. The silencing complex binds to and destroys an mRNA molecule that contains a base sequence complementary to the miRNA. In this way, it blocks gene expression.
The central dogma of molecular biology has been: DNA makes RNA; RNA makes proteins. Proteins carry out the bulk of functions involved in running a living organism.
Women are not necessarily healthier than men. Women on average do live 5-10 years longer than men because women have the XX chromosomes and men have the XY chromosomes. This matters because the X chromosome contains microRNA (small strands of ribonucleic acid). MicroRNA tells our genes what or what not to do. MicroRNA also plays a role in our body's immune system which can help ward off infections and cancer. A lot of this microRNA is contained in the X chromosome, basically doubling women's chances.
Genomic DNA: This is an information molecule. It stores directions on how to do various cell processes. It is a "hard-copy" molecule and if destroyed or altered, will likely have bad effects on the cell. It is not directly usable. If its directions are needed, the DNA is temporarily transferred onto the single stranded mRNA molecule. mRNA (messenger) : This is an information molecule as well. It stores the information about how to make proteins. It gives the order of amino acids through nucleotide triplets called codons. tRNA (transport) : This is not an information molecule. Its purpose is to "shuttle" amino acids to ribosome during protein synthesis. rRNA (ribosomal) : This is a structural molecule. The ribosome is largely made up of rRNA. snRNA (small nuclear): These are involved in RNA splicing, the process of cutting useless parts of RNA out. (When RNA is first copied off DNA, there are a lot of useless parts that need to be removed before the RNA becomes usable.) microRNA: These are regulatory molecules. They are very short, and bind to sequences on mRNA to inhibit translation.
There are two mechanisms as related to above. Firstly, the removal of All Introns occurs - via the Spliceosome -, and then a "poly AAAAAAA" tail is attached to the [edited] mRna transcript just before its export to the cytoplasmic Ribosomes.
According to "Elementary Biochemistry" by J. Davies and B. Shaffer Littlewood, mRNA contains 100-5000 N-containing bases, which is also the # of nucleotides. I guess the size of the mRNA is related to the size of the protein molecule that is being synthesized. What is the largest protein made in the human body?
mRNA