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That depends on the flow through the clog. The sulfuric acid-based cleaner will have little effect on the clog if an equivalent quantity of sodium hydroxide-based drain cleaner remains because the two will neutralize with little heat, to form salt water. If you graduated from a US high school, you should be able to balance the equation with regards to mass of the reactants:

2NaOH + H2SO4 -> H2O + Na2SO4

Oh, sorry, you slept through chemistry and don't know what I'm talking about? They told me that every child could learn chemistry when I was a high school teacher.

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Q: How long should you wait to use a sulfuric acid drain cleaner after using a lye drain cleaner?
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