Yes. There is scientific evidence to indicate that Halothane is able to induce cytochrome P450. P450 in turn anaerobically reduces halothane to potentially toxic metabolic compounds that cause liver damage
The human cytochrome P450 comprises 57 genes. These genes code for enzymes that can have a role in: metabolism of drugs, foreign chemicals, cholesterol metabolism and more. P450 was once thought to be mainly a hepatic drug detoxication system, its now believed to include a myriad of enzymic reactions implicated in important life processes.
Redox cytochromes and the P450 class of detoxifying cytochrome are enzymes which contains iron.few other classic examples are: Haemoglobin (carries O2 and CO2), Ferritin protein (stores ferrous).
Cytochrome c, or cyt c (horse heart: PDB 1HRC) is a small heme protein found loosely associated with the inner membrane of the mitochondrion. It is a soluble protein, unlike other cytochromes, and is an essential component of the electron transfer chain. It is capable of undergoing oxidation and reduction, but does not bind oxygen. It transfers electrons between Complexes III and IV. http://en.wikipedia.org/wiki/Cytochrome_c
I think your answer is both pepsin, a secreted inactive form of pepsinogen, and mucus.
Yes. There is scientific evidence to indicate that Halothane is able to induce cytochrome P450. P450 in turn anaerobically reduces halothane to potentially toxic metabolic compounds that cause liver damage
Cimetidine
Cytochrome P450 allows phenytoin to undergo aromatic hydroxylation to turn into phenol.
The human cytochrome P450 comprises 57 genes. These genes code for enzymes that can have a role in: metabolism of drugs, foreign chemicals, cholesterol metabolism and more. P450 was once thought to be mainly a hepatic drug detoxication system, its now believed to include a myriad of enzymic reactions implicated in important life processes.
Cytochrome P450 allows amphetamine to undergo oxidative deamination.
Karen Grierson has written: 'Role of the inducible cytochrome P450 isoenzymes in the metabolism of melatonin'
Cytochrome P450 allows phenobarbitual to undergo aliphatic hydroxylation. It then turns into an alcohol.
Kathryn Elizabeth Brocken has written: 'Cytochrome P450 isoenzyme activities in dog'
Cytochrome P450 and CYP2D6 allow codeine to undergo O-demethylation to form morphine.
Thuong Hoang has written: 'Expression of cytochrome P450 1B1 in preneoplastic conditions of the colon and cervix'
Kelly L. Cozza has written: 'Quick guide to the Cytochrome P450 system' -- subject(s): Cytochrome P-450, Drug interactions, Drugs, Handbooks, manuals, Metabolism
In the liver, heme is a component of several vital enzymes, particularly cytochrome P450, involved in the metabolism of chemicals, vitamins, fatty acids, and hormones.