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point mutation, insertion and deletion
Because a point mutation is the replacement of a single base with another base. Thus, if the replacement base codes for the same type amino acid, such as a hydrophobic type amino acid replacing a hydrophobic amino acid, no change to the protein coded for will occur. If a deletion mutation occurs then the code for the protein is disrupted and the protein product is probably going to be useless to the body and may even cause a disease.
PKU (phenylketonuria) is a point mutation, specifically an autosomal recessive genetic disorder caused by a mutation in the PAH gene. This mutation leads to impaired metabolism of the amino acid phenylalanine. It is not a frameshift mutation, which would involve an insertion or deletion of nucleotides, shifting the reading frame of the gene.
during meiosis
An insertion mutation is when an extra nucleotide is inserted into the DNA molecule.For example if the original sequence is:AATGCATGGACTan insertion could be:AATCGCATGGACTThis would change the code from: AAT GCA TGG ACTto AAT CGC ATG GAC T.....You can see that after the insertion all the codes are changed. Since each set of three nucleotides codes for an amino acid, this would change all of the subsequent amino acids in the protein coded for by the gene.
point mutation, insertion and deletion
Three types of gene mutations are substitution, insertion, and deletion. Another gene mutation would be frame shift. All these mutations can cause deformities of the gene.
Missense mutation Nonsense mutation Frameshift insertion Frameshift deletion All may cause antibiotic resistance in bacteria
Because a point mutation is the replacement of a single base with another base. Thus, if the replacement base codes for the same type amino acid, such as a hydrophobic type amino acid replacing a hydrophobic amino acid, no change to the protein coded for will occur. If a deletion mutation occurs then the code for the protein is disrupted and the protein product is probably going to be useless to the body and may even cause a disease.
PKU (phenylketonuria) is a point mutation, specifically an autosomal recessive genetic disorder caused by a mutation in the PAH gene. This mutation leads to impaired metabolism of the amino acid phenylalanine. It is not a frameshift mutation, which would involve an insertion or deletion of nucleotides, shifting the reading frame of the gene.
In the DNA, the sequence of nucleotides determines how proteins are built, with each segment of three nucleotides encoding a single amino acid. When one nucleotide is inserted into the sequence, the whole sequence shifts, and all the triples are changed completely, which can cause detrimental mutations.
An error in the repair of damaged DNA-Apex
Insertion mutations can affect many amino acids in the protein.An insertion mutation usually causes more defects during protein synthesis than point mutation because an insertion mutation will affect many amino acids in the protein.
3 cause 3 nts corresponding to an amino acid so it wont effect all the following code after insertion
Insertion mutations can affect many amino acids in the protein.An insertion mutation usually causes more defects during protein synthesis than point mutation because an insertion mutation will affect many amino acids in the protein.
during meiosis
The types of point mutations are: base-pair substitution, insertions, deletions, and frameshift mutations. In base-pair substitution, one nucleotide and its corresponding partner are replaced with another pair of nucleotide. In insertion, nucleotide pairs are added to a gene. In deletion, nucleotide pairs are taken out of a gene. Frameshift mutation happens as a result of insertion or deletion when more or less than three (or a multiple of three) nucleotide pairs are added to or taken from a gene.