About 70,000 Americans have it. About 2 million carry the gene for it.
how many chromosomes are in sickle cell
Sickle cell anemia was discovered in the 1870's and carried many names, but 1922 it was officially named sickle cell anemia.
Sickle cell anemia provides resistance to malaria - it is ideal for many people in Africa that live in mosquito rampant areas.
Sickle cell anemia comes as the result of having two sickle cell chromosomes. One sickle cell chromosome makes people resistant to malaria. Unfortunately when people have two sickle cell chromosomes they can get sickle cell anemia. That makes it difficult for their blood to carry oxygen and under certain conditions makes their blood clump. The disease can be deadly. Drugs can help. It probably makes that person resistant to malaria. The sickle cell trait evolved in various places around the world where malaria is common such as Africa and Greece.
Just one incorrect amino acid prevents protein from functioning properly in sickle cell anemia.
Sickle-cell is inherited from parents just as physical traits. People with the disease are SS type and show the anemia. Others can carry the trait (Ss). They are able to fight off malaria. Since this type (Ss) is important in areas with many malaria cases, this is protective.
It is a genetic disorder. However... It is also a protection against malaria. For example, if a person were born in an area where malaria is present, he or she would likely die from the disease, unless he or she inherited 1 sickle cell gene. Malaria viruses reproduce in the red blood cells. The parent virus invades a cell, and uses the cell as a host to grow more viruses. With 1 sickle cell gene, malaria viruses that invade a red cell are quickly destroyed, since the red cell collapses, preventing the virus from reproducing. But with 2 sickle cell genes, red cells collapse too easily; just a bruise can cause someone to become anemic when too many red cells collapse. In the real world, people with no sickle cell genes died from malaria. People with 1 sickle cell gene survived. People with 2 sickle cell genes died from sickle cell anemia. It was natures way of assuring that at least half of the population survive, but it is certainly a difficult thing to live with today, now that we can more easily treat malaria.
million people have sickle cell world wide i think
I have sickle cell and scapular necrosis occurred because the none in my joints became soft from the many crises I had. My teeth also was affected and severe decaying occurred. My dentist said it was because of the necrosis and sickle cell.
15000 people with sickle cell in the UK i think
Neither. People with sickle cell anemia have the same number of chromosomes and even the same number of genes as those who don't have the disease. The difference is a *change* in one of the genes. Actually, it is (usually) caused by a one letter difference in the hemoglobin gene which makes the hemoglobin produced more 'sticky' on a molecular level.
many conditions. few include thalassemia, acute blood loss, sickle cell anemia, vitamin B12 or folic acid or iron deficiency, post infection anemia, hereditary spherocytosis.