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How the karyotypes of klinefelter syndrome differ from the normal karyotypes?
Wiki User
∙ 16y ago
The karyotype of a person with Down syndrome differs from a normal karyotype because it contains a three chromosomes in the 21st slot, where there should only be a pair of two. That is why this is called Trisomy 21.
Wiki User
∙ 16y ago
Wiki User
∙ 16y agoKlinefelter's syndrome is characterized by a third sex chromosome. An individual with Klinefelter's has two X chromosomes and one Y chromosome. Therefore, a karyotype of Klinefelter's would have forty-seven chromosomes, the additional chromosome with the sex chromosomes.
Wiki User
∙ 16y agoYou can't really discern the difference of a non-hemophiliac karyotype and that of a person with hemophilia because this condition only affects a small part of the X chromosome.
Here's a picture to give you an idea of what area of the chromosome is affected by hemophilia.
http://www.mayoclinicproceedings.com/images/8011/8011gcp-fig2.jpg
The sections vary depending on the type of hemophilia. Hemophilia A (shown in the picture) affects the factor VIII gene, B affects factor IX, and C affects factor XI.
Wiki User
∙ 10y agoThe karyotype of someone with hemophilia is the same as that of someone without hemophilia. Hemophilia is caused by a mutation in one gene, not a chromosomal abnormality.
Wiki User
∙ 15y agoPeople with Klinefelter syndrome have one more chromosome than the normal male. I believe it's XXY instead of XY.
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Is klinefelter's syndrome a abnormality?
Klinefelter's syndrome is not considered to be a variation of normal, so by definition it is abnormal.
What are the genotypes of two parents that pass on the klinefelter's syndrome?
The parents have normal genotypes, because Klinefelter's syndrome is not inherited.
Does the Y chromosome in Klinefelters syndrome look like the X chromosome?
No. People with Klinefelter's syndrome have a normal Y chromosome and 2 normal X chromosomes.
Is Klinefelter's syndrome the same as Down syndrome?
Klinefelter = XXY Turner's = X Klinefelter syndrome is the extra X and can lead to somewhat of a female secondary sexual characteristic in men. Turner's is the single X some women receive and can cause short stature and lack of secondary sexual characteristics.
How many chromosomes are in klinefelter's syndrome?
It is estimated that about in in 500 men have Klinefelter's syndrome.
Is the karyotype of a person with schizophrenia normal or abnormal?
The majority of people with schizophrenia have normal karyotypes. If the karyotype is abnormal, it will be a coincidence and not the cause of the schizophrenia. For example, you can have Turner syndrome (1 X chromosome) and schizophrenia at the same time, but the Turner syndrome wouldn't have caused the schizophrenia.
Klinefelter's syndrome and XXY males are conditions that are caused by?
Normal humans have 46 chromosomes (23 from each parent). Males with Klinefelter's Syndrome have 47 chromosomes and therefore have acquired an extra chromosome from a parent (hopefully a more knowledgeable contributor will say if it is from the male or female parent). A lot of studies have been done on the male calico cat. Back in the 1980's if one found a male calico cat that was NOT sterile, the cat was worth about 30K... a lot of money for that time period. I am not sure if similar hunts are currently underway.
What is the future look out for people with klinefelters syndrome?
Most of the Klinefelter Syndrome affected persons can lead a life which could be considered as normal. However, they might have certain problems related to sexual organs, (among others), and some, - but not all -, could be infertile. The reason for this is their extra chromosome. Females have XX chromosomes, Males have XY chromosomes, and Klinefelter syndrome affected males have XXY chromosomes. They often are prescribed testosterone therapy. More info could be found on related links.
Is klinefelter syndrome sex-linked?
Males with Klinefelters, often have lower testosterone & additional breast tissue, weaker muscle tone. Sexual function is usually normal but Low sperm count is also common.
What is trisomy-21 klinefelter syndrome and turner syndrome?
All 3 conditions occur when non disjunction occurs in meiosis of the parent when they are producing gametes (egg or sperm). In normal meiosis, each parent gamete has 1 copy of each of the 22 somatic chromosomes and 1 sex chromosome. Non-disjunction occurs when 2 chromosomes go to one gamete and 0 go to the other. Trisomy 21 (Down Syndrome) is when the zygote has 3 copies (instead of 2) of chromosome 21. Klinefelter Syndrome (47 XXY) is when the zygote has 2 X chromosomes and one Y (a normal male is XY and a normal female is XX). Since they do have the Y chromosome, they are phenotypically (physically) male. Turner syndrome (45 X) is when the zygote has only 1 sex chromosome (X chromosome). They are phenotypically male.
Describe how the karyotype of an XXY human would differ from that of an XO human?
The karyotype of an XO human would be deficient one X chromosome, compared to that of a normal female, and it would result in a female. Normal human females only use one X chromosome, whereby one is inactivated, which is why an XO human is viable. An XXY human would have one extra X chromosome as compared to that of a normal male, and it would result in a male. Again, an X chromosome is inactivated, which is why an XXY human is viable. XO is referred to as Turner Syndrome. XXY is referred to as Klinefelter Syndrome.
What are the genetics behind Klinefelter's syndrome?
Klinefelter Syndrome is not caused by genes but is rather caused by chromosomal nondisjunction, or an odd number of chromosomes. Klinefelter Syndrome is particularly the presence of more than one X chromosome in a male's karyotype in addition to one Y chromosome (normal males have one X and one Y). Typically, a Klinefelter patient will feature the XXY karyotype, although the presence of additional X chromosomes has been reported. The adverse phenotypes associated with Klinefelter Syndrome are due to complications arising from gene dosage, or the amount of gene expression, not due to the presence of a certain gene or mutation.
