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Is M. tuberculosis acid fast or non-acid fast?

Updated: 10/26/2022
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Microbiostudent

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12y ago

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Mycobacterium tuberculosis is an acid fast bacterium. It has a high concentration of mycolic acids in the plasma membrane which prevent its staining by typical Gram stain methods. It must be stained with a procedure containing an acid decolorizing step to best visualize it under the microscope (Ziehl Nielson or Kinyon Methods). It resists decolorization with the acid, which is where the term "Acid Fast" comes from....

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Q: Is M. tuberculosis acid fast or non-acid fast?
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Saprophytic mycobacteria are acid fast and do not cause serious disease.


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