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Yes. I own a Ruger M77 Hawkeye in 280 Rem. It plain levels whitetails out to 200 yds, with a 140 gr. bullet. My only suggestion is that if you don't reload, start. 280 Rem is not as popular as the 270 Win or the 30-06 Sprfld, so ammo is not as readily available.

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Q: Is a 280 Rem. rifle a good caliber for hunting whitetail deer in North Carolina?
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