Haldane effect
internal respiration
PO2 can be estimate of dissolve O2,PO2 keep the oxygen on hemoglobin so if there is increase affinity of oxygen then required PO2 willbe low.each HB carry 20vol% O2 per 100ml of blood in a 100% saturation.if the dissolve oxygen become less then PO2 also become less in order to deliver more dissolve form to tissues.actua;;u ddissolve O2 at 100mmhg of PO2 is 0.3vol%/100ml of blood
It defuses throught the respiratory membrane and binds to hemoglobin (in humans) following a hemoglobin type-specific binding affinity curve (depending on the Po2 of the local atmosphere.)
Bohr effect. Incorrect. It is not the Bohr effect...it is actually the "Haldane effect"=The lower the PO2 and the lower the extent of hemoglobin saturation with oxygen (O2), the more CO2 can be carried in the blood. This phenomenon is called the Haldane effect. As per the Human Anatomy and Physiology eighth edition text book published 2010.
The primary factor that determines how much oxygen is actually bound to hemoglobin is the partial pressure of oxygen (pO2) in the hemoglobin solution.
Assuming the Ka= [H+][PO2-]/[PO3-] and that PO3=PO2- then we can safely assume Ka= [H+][PO2-]/[PO2-] and so Ka= [H+][PO2-]/[PO2-] Ka=[H+] since the Ka of Phosphoric acid is equal to 7.5x10-3 then we can take -log(7.5x10-3) to find the pH=2.12
Rather than a blood vessel with a value of 104mm Hg for Po2, it is alveolar gas thatt has a Po2 of 104 mm Hg
PO2 in blood is the amount of gases in your blood. In medical terms, this is commonly called the Alveolar-arterial.
In the lungs where the oxygen concentration is high the binding of oxygen tohemoglobin is high. In respiring tissue where the oxygen levels are low and the CO2 levels are high the affinity of hemoglobin for oxygen is reduced and so the oxygen comes off the hemoglobin and is used by the cells. The driving force for this is the Bohr Effect whereby CO2 produced by the respiring cells dissolves in the blood as follows CO2 + CO2 --> H2CO3 --> H+ + HCO3-. The H+ produced bind to the hemoglobin and in doing so displace the oxygen
PO2(OH)2 is the same as H2PO4^- (note the negative charge). It would be dihydrogen phosphate.
Pulmonary artery/Systemic veins PCO2 = 45 PO2 = 40 Pulmonary vein/Systemic arteries PCO2 = 40 PO2 = 100