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Yes, they interact well in fact, but not in excess. I took 120 mg of Adderall during the course of 24 hours, and took two 25 mg phenergan half way through that. I was tripping the entire next day after already staying up a day and taking the stated drugs. Seeming to be able to shut off the morphing hallucinations whenever I wanted to be fully alert. The combination reminded me of acid, but more of a dream like acid state.

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14y ago
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14y ago

NO its not OK and may lead to an overdose. Phenergan is an antihistamine which will make codeine markedly more potent, which can lead to and overdose. Do not mix opiates with antihistamines such as Phenergan, Benadryl, etc. Also avoid grapefruit juice. Mixing just codeine and Adderall isn't advisable either. Adderall is an upper, codeine is a downer. While mixing a downer and an upper is alot safer than mixing an downer and a downer, or upper and an upper, its not good for your health. It won't kill you, but it wont do any good for your health. Adderall itself is unhealthy to be on and increases you chance of caridac problems and sudden death.

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Q: Is it ok to mix Adderall and phenergan with codeine?
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