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Depending on the medication, it is usually safe to use a migraine medication everyday. However, it is not wise to do so. Taking either abortive migraine medications or pain medications (and this includes Tylenol and Excedrin as well as prescription pain relievers), can cause a situation where not only does the medication stop working, but you get caught in a daily headache cycle. And the only way to break that cycle is stop taking the medication completely for up to three months.

The golden rule is to not take your migraine abortive or pain medication more than 2-3 times a week or more than half the days in the month.

Note: The above is assuming that you are taking the recommended dose. Keep in mind that acetaminophen (Tylenol) is declared safe when you take up to 4000mg a day (in divided doses), even taking 3000mg daily can harm the liver. It is important to be aware of all the Tylenol you are ingesting, as it is in many, many medications. Any time you read APAP on your prescription bottle, it contains generic acetaminophen.

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βˆ™ 15y ago
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βˆ™ 11y ago

You should always follow the label instructions unless your doctor gives you alternative instructions. Taking this drug daily can be dangerous. It can cause liver and organ problems or failure and can result in Medication Overuse Headache (MOH). See your physician or headache specialist for appropriate diagnosis and treatment of Migraine and headache disorders.

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Q: Is taking Exedrin migraine daily dangerous?
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