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Alcohol binds to the GABA (gammabutyric acid) receptors in the brain. GABA is the major inhibitory neurotransmitter in the brain. When blood alcohol levels decrease, there is less GABA activation, and therefore more excitation in the brain (via the glutamate neurotransmitter system). This causes tremors, tachycardia (fast pulse) and hypertension (high BP) to occur, along with other symptoms. This process can be reversed by activating GABA once again, either by drinking alcohol or going through detoxification with GABA activating medicines in the benzodiazepine class (Valium, Ativan, and the like).

The problem with drinking alcohol in the morning is that it can lead to a vicious cycle of chronic intoxication (and withdrawal) states. When alcohol is used to treat withdrawal symptoms ("hair of the dog that bit you"), more alcohol per day is used, often leading to tolerance and dependence. Treatment for this cycle is best accomplished by detoxification, counseling, and abstinence.

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Q: Is there a medical reason behind having a drink in the morning to cure a hangover?
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