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I found there to be a negative synergism as one who was prescribed both at the same time earlier in treatment for bipolar. The provigil was used to combat side effects of drowsiness from depakote. As a recovering drug addict, i felt that the provigil made me feel extremely anxious, and would compare the feeling to the anxiety of drinking way too much caffeine or taking too much adderol or cocaine. Of course, the provigil helped me feel not drowsy, but not drowsy to the point of panic, paranoia, and anxiety. This is my personal experience and I'm also not a doctor. Discuss anything of this nature with a doctor always. Depakote has always worked for me, aside from some side effects, but the addition of the Provigil made me a little crazy. I would be careful taking it. I was also quite wary of the drug Provigil when i found out that the original use for it was too keep soldiers in Irag awake for extended periods of time!! Sounds scary.

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Q: Is there a negative synergism between Depakote and Provigil?
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The clinical trial studied the synergism between hormones and the prescription drugs. Adherents of religious synergism suggest that believers must cooperatively determine their own destiny.


Can you take provigil and ultram together?

Yes, of course. There are no drug interactions between the two.


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yes, DR is a sealed enteric coated large oval tablet, sprinkle is a capsule intended to be opened and the contents sprinkled on food.


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from what i have recently read on it Provigil has a short half-life in your body, however when it comes to drug tests Provigil can stay in your system up to a few days after it is taken, however it typically only shows up on blood and urine samples, and not typical employment drug tests. Hope this could help, I'm still tyring to figure some stuff out too!! Maggie from what i have recently read on it Provigil has a short half-life in your body, however when it comes to drug tests Provigil can stay in your system up to a few days after it is taken, however it typically only shows up on blood and urine samples, and not typical employment drug tests. Hope this could help, I'm still tyring to figure some stuff out too!! Maggie


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