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There is a chance that even small amounts of quinine, the bittering agent in tonic water, can cause side effects from diarrhea, to blindness, and in rare cases--pulmonary edema, possibly resulting in death. While casual consumption of tonic water seldom results in more than the mildest of side effects, prolonged and heavy consumption can build to intolerable levels resulting in renal failure.

It should be noted that levels of quinine in tonic water are minute as compared to therapeutic doses and evidence that drinking tonic water for cramps or other preventative measures cannot be confirmed.

For further information explore Quinine Toxicity.

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Q: Is too much tonic water bad for you?
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