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More basic nitrogen in purine

Updated: 9/18/2023
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Purine is weakly basic in nature (pKa 2.5). 13C NMR studies of the protonated purine indicate the presence of all three protonated forms of purine in solution. However, the predominant cation is formed by protonation at N-1.[J. Org. Chem. year: 1965, Vol.: 30, page: 1110] In strong acids, dication is formed via protonation at N-1 and on the five membered ring.

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Q: More basic nitrogen in purine
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What change in the sequence of nitrogen bases in genes?

Mutation. . Either exchanging a Purine with another Purine, Pyrimidin with another Pyrimidin, or completely exchanging a Purine with a Pyrimidin or vice versa. Point- or Frameshift-Mutat


Why Imidazole is more basic than pyrazole?

Presence of two nitrogen in the ring of imidazole makes 2 more electrons available fr the donation hence makin it more basic then pyrazole


Why is dimethylamine more basic than trimethylamine?

ethylamine is more basic than dimethylamine because the former one allows nitrogen atom to take reaction without any hindrance(prevention) of this reaction to occur.The later one has methyl groups on both sides of nitrogen atom,these groups hind nitrogen atom from reacting weth electrophiles.Remember nitrogen determine reactivity of amines.


What elements is nitrogen mostly made out of?

Nitrogen is not made out of anything, it is an element and therefore as basic as it gets.Two nitrogen atoms make up a nitrogen molecule.


Which is more basic cyclohexyl aniline or aniline?

Strength of bases is related to the ease of accepting a proton which inturn depends on the availability of electron pair on the nitrogen atom (or some other basic atom). More is the availability of electron pair, more easily the proton will be accepted and more will be the basic strength.Aniline is a weaker base than ammonia or cyclohexylamine. It is because of the fact that the electron pair on nitrogen is involved in delocalization, making it less available for donation.

Related questions

Is nitrogen a base?

A basic compound that contains nitrogen, such as a purine or pyrimidine. A basic compound that contains nitrogen, such as a purine or pyrimidine.


What are the elements of a nitrogenous base?

A basic compound that contains nitrogen, such as a purine or pyrimidine. A basic compound that contains nitrogen, such as a purine or pyrimidine.


Where a purine base only pairs with a pyrimidine?

nitrogen


What change in the sequence of nitrogen bases in genes?

Mutation. . Either exchanging a Purine with another Purine, Pyrimidin with another Pyrimidin, or completely exchanging a Purine with a Pyrimidin or vice versa. Point- or Frameshift-Mutat


Purine nucleotides mainly differ from pyrimidine nucleotides in their number of?

Nitrogen rings in the base


Adenine is an example of a?

Adenine is an example of a nitrogen base that is found in DNA and RNA.


Is transversion of t to an equivalent to transversion of t to g For example is T961a the equivalent of T961g?

Transversion is the substitution of a purine for a pyrimidine and vice versa. The nitrogen bases adenine (A) and guanine (G) are purines and the nitrogen bases thymine (T) and cytosine (C) are pyrimidines. The transversion of T to A is equivalent to the transversion of T to G in that a pyrimidine, T, is substituted by either the purine A or the purine G. T961a is not equivalent to T961g.


What does purine mean?

A purine is a nucleotide in DNA that only has 1 ring.


What the three parts of a nucleotide?

Nucleotides are made up of three basic components: a 5-carbon sugar called deoxyribose in DNA or Ribose in RNA , a phosphate group, and a nitrogenous (nitrogen-containing) base Purine ( Adenine , Guanine ) or Pyrimidine ( Cytosine , thymine , Uracil .)


Why Imidazole is more basic than pyrazole?

Presence of two nitrogen in the ring of imidazole makes 2 more electrons available fr the donation hence makin it more basic then pyrazole


What are the three pyrimidine bases?

There are 2 groups of nitrogen bases. These are Pyrimidine and Purine. In the Purine group, there are Adenine and Guanine, In the Pyrimidine group, there are Cytosine, Thymine(replaced by Uracil in RNA).


Why is dimethylamine more basic than trimethylamine?

ethylamine is more basic than dimethylamine because the former one allows nitrogen atom to take reaction without any hindrance(prevention) of this reaction to occur.The later one has methyl groups on both sides of nitrogen atom,these groups hind nitrogen atom from reacting weth electrophiles.Remember nitrogen determine reactivity of amines.