0
Nitrofurantoin method development in lcmsms and linearity range?
Wiki User
∙ 12y ago
LCMSMS-3200
LINEARITY RANGE:5-800 ng/mL
EXT PROCEDURE:0.250 mL +50µL ISTD(Nitrofurantoin 13c3)+2.5 mL Ethyl acetate)-vortex,centrifuge and transfer 2.0 mL supernaunt and evaporate till dry at 40C and reconstitute 0.250 ml Mobile phase(10 mM ammonium acetate :MeoH-5:95)
column:phenyl column-c18
Wiki User
∙ 12y ago
Add your answer:
Earn +20 pts
Why calibration curve method is more reliable as compared to a single point method?
Why Calibration curve method is more reliable than single point method?Read more: Why_Calibration_curve_method_is_more_reliable_than_single_point_method
What is the significance of the development of the cyanmethemoglobin method?
ewan ko sayo,assignment mo yan eh...
Why did Richard R. Schrock win The Nobel Prize in Chemistry in 2005?
The Nobel Prize in Chemistry 2005 was awarded jointly to Yves Chauvin, Robert H. Grubbs and Richard R. Schrock for the development of the metathesis method in organic synthesis.
Why mohr method is better than volhard method?
because mohar method gives the accurate result
The periodic table in scientific method?
it is a scientific method NOVANET
Linearity is how much important in method validation?
its important for recover the calculation equation and for improve linearity equation (pears low )
How many parameters will perform in analytical cleaning method validation?
linearity, Recovery for soaping , recovery for stainless plate and LOD & LOQ
What is the definition of method development by hplc?
Method development is a process amenable to continuous improvement
What is adhoc system development method?
this is the development of a system as at when it is required.
How to Calculate Pressure Transmitter Accuracy?
accuracy with only one variable. Accuracy takes into account several different variables, only one of which is non-linearity. In other words, non-linearity alone does not determine a device’s overall accuracy. These are the five variables a user should consider when determining pressure transmitter accuracy: Two methods are used to generate the reference line needed to find a pressure transmitter’s non-linearity: the terminal method, also called endpoint method (blue line) and the best fit straight line method (brown line). The linearity is the largest deviation from the reference line to the actual response (red line). Non-linearity Non-linearity is the largest deviation between the actual response (red curve) and a reference line. There are two common methods for generating this reference line The terminal method, also called the endpoint method, draws a straight line from the actual zero point to the actual full scale value endpoint. Since this method is based on the characteristic curve’s endpoints, it is a truer representation of a pressure transmitter’s non-linearity. The best fit straight line (BFSL) method is a straight line that stays within a certain percentage deviation from the characteristic curve, or actual response. The endpoints do not figure into this method. BFSL method values are typically half of terminal method values, meaning that a pressure transmitter with a ±0.25% BFSL non-linearity allows for a ±0.50% error. Zero offset and span tolerance when calculating pressure transmitter accuracy Zero offset The zero offset is the deviation between the ideal line’s zero point and the characteristic curve’s zero point (see Fig. 4). Span tolerance Span tolerance is the deviation of the actual span from the ideal span between the zero point and the full scale point. The span offset is not related to the zero offset and has to be added to it. Hysteresis Hysteresis is the lag between a change in pressure and the corresponding change in the pressure transmitter signal. It is an indication of how fast or slow a pressure transmitter responds to input changes. Non-repeatability Non-repeatability is the maximum difference in the signal of the pressure transmitter for the same applied pressure. It is an indication of how much the transmitter duplicates measurements for the same input.
What is cadm?
CASE Application Development Method
What are the guidelines for method development of hplc according to ich?
the same guidelines for method validation
What is paragraph development by combined method?
combined paragraph development method is a type of methods in which at least 2 types of paragraph development methods are used . Clearly , mix of at least 2 other types .
Procedure adopted under the scientific method in development under the economic theory?
Describe the procedure adopted under the scientific method in the development of economic theories
What is the method for development of dish end plate fro pressure vessels?
how to development of dish end in auto cad
What is problem with traditional software development?
In traditional software development method there were only two steps that is build code and fix. This was not an efficient method so new life cycle models were introduced.
Can you display list of new drug combination for method development?
yes
