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Newer vehicles say they can do up to 7500 miles on a oil change. I would never do that though. The more frequently you change the oil the better it is for the vehicle no matter if it is a Mercedes or a Buick. I try to change mine at least no more than 5000 miles. I use sythetic oil and have been happy with the results. It is seems to start easier on those cold morings and also the synthetic doesnt break down near as easily as regular petroleum based oils. I hope this helps you. Good luck.

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Q: Oil change frequency on a 2003 Mercedes e class?
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