Although there are several things that can cause this code. The most common on the vortec is a bad distributor cap. When you replace the cap. Do NOT use a cheap cap and always use ac delco plugs in a vortec. They are very picky with ignition.
If you need it timed afterwards you will have to use a scan tool and set it plus or minus 2 degrees of 0 while watching the cam retard on the scan tool.
answer : Random Misfire
po300-Random/multiple cylinder misfire detected. po303-Cylinder no. 3 misfire detected. po306-cylinder no. 6 misfire detected po300-Random/multiple cylinder misfire detected. po303-Cylinder no. 3 misfire detected. po306-cylinder no. 6 misfire detected
Random cylinder misfire
Trouble code P0300 means:Random/multiple cylinder misfire detected
Trouble code P0300 means:Random/multiple cylinder misfire detected
Trouble code P0300 means:Random/multiple cylinder misfire detected
a po300 code is a random misfire code witch means it is not just missing on just one cly. witch kind of eliminates a ignition problem unless you have multiple ignition parts going bad more likely a fuel problem or vacuum leak
Most obdii codes are multi-digit, such as po300,po301,po302, etc. Etc. Po300's are usally misfire codes pertaining to the same cylinder...code po302 is a misfire in cylinder #2. A po300 code is a random misfire for any cylinder
misfire
the code means: random/multiple cylinder misfire detected, po300, it could be wires,spark plugs, bad coils, etc.
My book shows P0300=Random/Multiple Cylinder Misfire Detected. P0342=Camshaft Position Sensor Circuit Low Input. Hopefully this helps you out.
This just happenned to me. I was getting a code PO300. It turned out to be the ignition control module. It cost 78.00 at autozone and only took 10 minutes to replace.