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Activation, conversion from glycogen phosphorylase B to glycogen phosphorylase A

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KAMRAN

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Q: Phosphorylation of glycogen phosphorylase has what effect on the enzyme?
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Which enzymes are required for glycogen breakdown?

glycogen phosphorylase, glycogen debranching enzyme, phosphoglutomutase


Is the enzyme that catalyzes glycogenolysis always present in active form?

I think you're referring to glycogen phosphorylase, which is an enzyme that catalyzes the reaction where glycogen is turned into a glucose-molecule, therefore making it available for transformation to energy. Glycogen phosphorylase comes in two forms, A and B. Usually, the A form is considered the active form, whilst B is the inactive form. That is a modified truth, since both of these forms can exist in a T (tense) inactive state and R (relaxed) active state, depending on the presence of ADP (residue after phosphorylation of ATP). But usually, A is in its R state and B is in its T state. So for the sake of argument, we say A is active and B is inactive. So the short answer would be 'No'. For example, hormones such as epinephrine, insulin, and glucagon regulate glycogen phosphorylase. Essentially, epinephrine and glucagon promotes the A form (by activating phosphorylase kinase, an enzyme that transforms A into B), and insulin promotes the B form (by inhibiting the phosphorylase kinase).


When a cell needs energy's does it breaks down the chemical glycogen?

Glycogen is made and stored in the cells of the liver and muscles until it is needed for energy. Glycogen phosphorylase is the primary enzyme of glycogen breakdown into glucose. Glucose derived from liver glycogen is the primary source of blood glucose used by the rest of the body for fuel.


What enzyme regulates glycogenolysis?

Actually, three are the enzymes that intervene during glycogen breakdown (glycogenolysis).First, Glycogen phosphorylase (or simply phosphorylase) that catalyzes glycogen phosphorolysis (bond cleavage by the substitution of a phosphate group) to yield glucose-1-phosphate (G1P) releasing only one glucose residue that is at least five residues from a ramification point.The second enzyme is the Glycogen debranching enzymethat removes glycogen's branches, thereby permiting the glycogen phosphorylase reaction (see above) to go to completion. This enzymes also hydrolyzes alpha(1-6)-linked glucosyl units to yield glucose.Finally, Phosphoglucomutase that converts G1P to G6P which is also formed in the first step of glycolysis through the action of either hexokinase or glucokinase.


What are the three enzymes involved in the conversion of glycogen to glucose?

The process of "glycogenolysis" is the splitting of glycogen in the liver, which in turn produces glucose. Glucagon can be administered in emergency diabetic situations where sugar can't be taken orally.


What enzyme synthesises starch from glucose -1- phosphate?

this enzyme is called phosphorylase.


Example of enzyme responsible for a synthesis of a substance?

phosphorylase


What is Introduction to Glycogen Metabolism?

glycogen metabolism is the terminology used for both glycogen synthesis and glycogen degradation ,glycogenesis and glycogenolysis .both of these pathways are exactly opposite to each other because both of these pathways involve different enzymes glycogenesis is carried out by enzymes HEXOKINASE,PHOSPHOGLUCOMUTASE,UDP-GLUCOSE-PYROPHOSPHORYLASE,and GLYCOGEN SYNTHASE. glycogenolysis is carried out by enzymes GLYCOGEN PHOSPHORYLASE,PHOSPHOGLUCOMUTASE,and debranching enzyme (GLUCAN TRANSFERASE).


What is the effect of phosphorylation on enzyme activity?

Phosphorylated enzymes may be more or less active than non-phosphorylated enzymes


What is the specific definition of glycogen synthetase?

an enzyme that assists in the breakdown of glycogen


What enzyme catalyze the phosphorylation of glucose after a meal?

glucokinase


Which enzyme is responsible for the phosphorylation of creatine?

Creatine KINASE