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If patients with atrial fibrillation experience rapid heart rate (rapid ventricular response) and are hemodynamically unstable (hypotension, altered mental status) then electrical cardioversion is appropriate. Defibrillation is never utilized in atrial fibrillation.

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Q: Should emergency defibrillators be used on patients suffering atrial fibrillation attacks?
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Shrimp contain a moderate level purine and can be used in moderation for patients suffering from gout.


What is pharmacologic management of ventricular fibrillation?

Patients who experience ventricular fibrillation (which is disorganized electrical activity occuring within the lower chambers of the heart) are resuscitated via defibrillation. Defibrillation consists of an electric shock usually delivered via conductive pads or paddles. It essentially resets all the cells of the heart in hopes that when electrical activity resumes, it will be organized and able to pump blood. Untreated, all ventricular fibrillation is fatal, and patients who are at known risk for experiencing this arrythmia can be provided with an implanted cardioverter defibrillator, or ICD. This is a device which is placed under the skin of the upper torso and connected to the heart with a wire. It contains a computer which will monitor the patient's heart at all times and deliver a shock if recognizes ventricular fibrillation or a related rhythm called ventricular tachycardia. There are also certain drugs, such as amiodarone and lidocaine, which can be given to a patient at known risk for ventricular fibrillation in order to make it less likely. These drugs usually work by making the cell membranes of the cells of the heart more electrically stable. Many of the same drugs can also be given if defibrillation is initially unsuccessful in order to help make it more effective. It should be noted that there is a very short window of time to treat ventricular fibrillation (permenant brain damage begins to occur approximately 4-6 minutes after the onset of the arrythmia), and the prognosis for these patients is generally very poor if they are not defibrillated immediately and transferred to a critical care setting.


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What precautions should be taken in prescription of the implantable cardioverter-defibrillator?

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Why do patients with a heart rate greater than 160 not receive nitroglycerin for chest pain?

At this fast a rate, the heart chambers do not have adequate time to refill fully with blood. This is called fibrillation and is associated with a corresponding decrease in cardiac output and lower blood pressure. Since nitroglycerin also causes lower blood pressure by dilating or expanding the vessels, the additive effect could cause loss of consciousness.

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If you are a patient currently in atrial fibrillation. Generally speaking an adenosine or lexiscan nuclear stress tests are usually the best options. The other medicated stress test is Dobutamine (both echocardiogram and Nuclear). You do not want to use Dobutamine on patients at risk to go into atrial fibrillation because it is a drug that can induce it. For patients that are in chronic atrial fibrillation dobutamine can be used but is not considered to be as diagnostic as a lexiscan or adenosine stress test. The reason being (and this goes or exercise stress tests as well) dobutamine is a heart rate dependent test. This means the closer the heart rate gets to the patients age predicted max HR the more accurate the test is at detecting heart disease. The assumption in this is that the patient is in a sinus rhythm. Myocardial oxygen demand correlates directly with patients HR when the patient is in sinus rhythm. If the patient is in atrial fibrillation that correlation with myocardial oxygen demand becomes much more cloudy thus reducing the sensitivity of an exercise or dobutamine stress test with patients in atrial fibrillation. Both lexiscan and adenosine eliminate HR demands in detecting CAD which makes them the best test for a.fib patients.


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