Yes, by Alexander the great at around 330 BCE.
Persepolis, one of the four capitals, was burned down and stripped of its treasures on a side note.
Alexander the Great.
Macedonia conquered it through superior strategy and tactics.
Achaemenid Empire was created in 550.
Egypt was conquered by Cambyses II, the ruler of the Achaemenid Empire, the second of the four pre-Islamic Persian Empires
Alexander III the Great conquered the Persian Empire of the Achaemenid House between 334 and 331 BCE
The Achaemenid Empire.
Cyrus II of Persia (600 BC - 530 BC) established the Achaemenid Empire (c. 550-330 BC), which was the largest empire in history, and stretched from the Balkans in the west to the Indus Valley in the east. His successors Darius and Xerxes led the empire against the Greeks on several occasions. The Achaemenid Empire was partly conquered by Alexander the Great, and was succeeded by the Seleucid Empire.
The Achaemenid dynasty ruled the Persian Empire 559-430 BCE, after which it was taken over by the Macedonian King Alexander the Great.
An Achaemenid is a member of the dynasty which ruled the Persian empire between c. 550 - 330 BCE.
Long distance transportation, different languages and customs, and a diversity of religions were some of the challenges the Achaemenid Empire faced.
During the Achaemenid Period, there were four: Persepolis, Susa, Pasargadae, and Hamadan (ancient Ectabana).
The Achaemenid Empire.