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The causes of gastric ulcers include H. pylori infection, NSAIDs (Non-steroidal-anti-inflammatory drugs), stress, and malignancy. If malignancy is identified, surgical removal is undertaken. If H.pylori infection is confirmed (by culturing or by detection of circulating antibodies) appropriate combination antimicrobial therapy is instituted. Otherwise, H2 receptor antagonists or H+, K+-ATPase inhibitors are administered. Physiologically speaking, peptic ulcers arise due to an imbalance of acid secretory and mucosal protective mechanisms. About 20% of stomach ulcers are caused by NSAIDS such as aspirin, indomethacin, etodolac, ibuprofen, tolmetin, meclofenamate, etc. About 80% of stomach ulcers are caused by H. pylori (Helicobacter pylori), which is a bacterial infection. Summary of factors leading to stomach ulcers:

  • H. pylori infection.
  • Decreased mucous protection of stomach lining. Acid attacks unprotected stomach lining leading to ulcer.
  • Excessive use of NSAIDS.
  • The mucosal lining of the stomach is eroded.
  • Secreted HCl and pepsin attack the unprotected surface of the stomach.
  • Insufficient prostaglandin production.
  • Complicating factors: smoking, alcohol, stress.
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15y ago
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13y ago

stress, which causes too much stomach acid.

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Q: What are possible causes of stomach ulcers?
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Related questions

What effect does helicobacterium pylori has on stomach?

It is one of the main causes of stomach ulcers.


Which Scientists discovered what causes stomach ulcers?

1 million!


If you drinking alcohol over a long period of time where will it cause ulcers?

Alcohol, by itself, rarely causes ulcers. However, if you take it with aspirin or ibuprofin (Advil), both of which reduce the mucous that protects the stomach wall from stomach acid, the combination can lead to stomach ulcers.


What causes ulcers on the body?

Ulcer in the generic means a hole. All types of disease processes cause or may cause ulcers. Stomach ulcers, a subset, are typically promoted by bacteria.


What causes sores or holes that form in the lining of the stomach causing pain and bleeding?

Peptic ulcers


Will Paxil cause ulcers in the stomach?

does paxil medicine cause stomach ulcers?


What lesion can stomach acid caused?

Stomach ulcers, peptic ulcers, gastritis.


How do acid foods effect your body?

Acid foods when reach stomach it increases the concentration of HCl produced inside stomach which in turn causes ulcers inside stomach.


Which genus of bacteria causes stomach ulcers?

Heliobacter is the primary cause of stomach ulcers That should be spelled helicobacter. Specifically, the bacteria is called helicobacter pylori. The organism is helical and is found near the pyloric valve (between stomach and small instesine). pyloric = gateway (greek).


Can stomach ulcers be hereditary?

No, Stomach ulcers are caused by a bacteria. A course of antibiotics will cure the problem.


How the ulcers were cured?

stomach ulcers are cured by going to the doctors


Which is easier on your stomach oxycodone hydrochloride or acetaminophen with oxycodone?

Your first one Acetaminopen will take a toll on you liver after a while. It also know to upset the stomach as it causes ulcers