Sauternes is a very sweet dessert wine, so you could use Muscat de beaume de venise (also a dessert wine), some sherry or a sweet liqueur.
A subsitute in math is a number that replaces a variable For example: 2xA 2 is going to be the subsitute of A The answer: 2x2
a subsitute for alligator poo a subsitute for monkey poo a subsitute for any poo
No
No
A substitute for a noun is a pronoun.
I have heard that Allspice is an alternative.
any flour
aspartame
yes
yes it was
chicory
no there is no natural subsitute for a retin-a