There is a lot of speculation that Alexander died of poisoning from his own men, namely those who followed Cassander. Cassander, along with other Macedonians, Greeks resented Alexander for trying to incorporate those he conquered into his army, including marrying them off to "Asian" "Bactrian" or any other non-Greek woman.
Alexander himself married Roxanne, a Bactrian, which angered his close companions and army. However it seems that malaria is more than likely the culprit, after having contracted it while he was in India before heading back to Babylon where he died not long after. All the symptoms described in the history books suggest malaria.
If you can get past the camp and melodrama of the movie Alexander the story line shows that Alexander becomes increasingly "oriental" as in "Asian" (in the ancient world sense) as he travels with his army across the known world and incorporates those he conquers into his traveling army.
his death
Malaria
The death of Alexander the Great caused his unified empire to be split three ways under his top generals. This caused a great deal of unrest in what was Alexander's empire.
the great gap between rich and poor
Alexander the Great was the king of Macedon in 300 BC. What caused Alexander the Great to become a pharaoh is that he claimed land over two hundred years ago.
What caused the downfall of the Shang Dynasty was that Shang Zhou's army was defeated by the Zhou people at the Battle of Muye.
Malaria
Alexander the great
The death of Alexander the Great caused his unified empire to be split three ways under his top generals. This caused a great deal of unrest in what was Alexander's empire.
the great gap between rich and poor
Alexander The Great
The carefully planned and executed successful assault by Alexander the great.
Its defeat and takeover by Alexander the great.
Its defeat and takeover by Alexander the great.
the great gap between rich and poor
Alexander the Great took conquered it and took it over as his own empire.
Its defeat and takeover by Alexander the Great.
He died prematurely.