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The BRCA 1 and BRCA 2 mutations increase the risk of which cancer in women?
Yes, but the BRCA1 and BRCA2 tests can also be negative.
What does BRCA stand for?
BRCA1 and BRCA2 are genes that can mutate into cancer.
Where is BRCA testing done?
It's usually done in hospitals.
What mutagen causes breast cancer?
Well the onco genes are BRCA-I and BRCA-II if mutated they cause breast cancer, I think that is what you meant, if not then you may have learned something new anyway
What does BRCA mean?
BRCA1 and BRCA2 are two genes in your DNA which when altered or mutated, leads to Breast cancer.
How do the BRCA genes function differently in a person with the mutation?
The BRCA genes are involved in initiating DNA repair and cell cycle check points, they as as regulators of other tumour supressors genes such as p53 and help the cell repair and damage which may lead to cancer occurring in the cell. In mutant versions of the BRCA genes they cannot perform their roles and damaged DNA may cause the cell to replicate uncontrollably as check point to prevent this has been removed. Genome stabiliy is affected and cancer can develop
What is the genetic basis of cancer?
Some cancers show a genetic predisposition - for example BRCA Mutation a form of breast CA.
Is breast cancer disease genetic communicable enviromental oe behavioral?
Breast cancer has a bit of all.The genetic cases only make up around 5% of all cases (check out BRCA 1 and BRCA 2 genes).The environment definitely impacts on it (eg. smoking).I guess behavioral falls into environmental.However, the great majority is just random, that's why it's important to get screened regularly, espacially for women over 40.
Is the test BRCA 12 done at Tata Memorial Hospital If yes what is the cost of the test and what specimen has to be sent and where?
You need to speak to a certified genetics counselor. The test ranges from 300 to 3000 dollars depending on which panel you have done (a cgc can help you decide) There's a website called FORCE (facing our risk of cancer empowered) that is specifically for people with increased risk of breast and ovarian cancer...they can answer just about any question you have abour brca 1 and 2...good luck!
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