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mRNA that includes introns due to errors in mRNA processing will generate dysfunctional or truncated proteins. If the intron introduces a stop codon in the middle of the sequence a truncated protein will be produced. If the intron does not introduce a stop codon the end result is still going to be a protein with many unnecessary amino acids that will most likely interfere with folding and stop it from becoming functional.
Wiki User
∙ 13y ago
Wiki User
∙ 12y agoIntron RNA will be degraded in the nucleus. There is no other way: they can't just be piling up in there. The base pairs released as a result of this degradation are used in transcription to create a complimentary mRNA strand.
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What do you mean by splicing in electronics?
Splicing means joining in optical fibers.a process called splicing takes place to join two fibers.
Can you compare gene splicing with gene cloning and recombinant DNA?
Splicing is a cellular process where the DNA sequence is 'edited' before RNA is synthesised from it. This means that one DNA sequence can create different proteins. Sections that are spliced out are called introns, while exons are the sequences that remain. Prokaryotic organisms do not splice their genes, the DNA is copied directly to RNA. Since many biotechnological procedures use bacteria (prokaryotes) to test eukaryotic genes, the sequence needs to be 'spliced' before it can be expressed correctly by the bacterium. To do this researchers isolate the RNA (which lacks the introns) and convert it back to DNA, using reverse transcriptase. They then use this cDNA (complementary DNA) to express in the bacterial system. This is effectively recombinant DNA, because it does not occur naturally in the source organism.
What is splicing enzyme?
spliceosomes
In advantage of using reverse transcriptase to prepare a gene for cloning is that?
the resulting DNA strand will lack introns
Why is splicing of optical fibers done?
Splicing of optical fiber cable is done to extend a cable, making it longer, or to repair a break in it. Splicing is preferred over installation of connectors, because the connectors introduce losses and degrade reliability. Some connectors are necessary, but those are placed in a protected environment, and their use is minimized. Besides, a typical cable, with 56 or more strands, would require 56 or more connectors, and that would create a large lump in the cable.
What is the process called which removes introns from RNA?
RNA splicing
RNA splicing involves the?
removal of introns from the molecule :)
What is the role of introns in gene regulation?
Introns are removed through RNA splicing. They don't play a role.
How do introns and exons relate to RNA splicing?
Before the RNA leaves the nucleus, the introns are removed and the exons are joined together, producing an mRNA molecule with a continuous coding sequence. This process is called RNA splicing.
What is the primary transcript of eukaryotic genes?
the primary transcript usually has a exons and introns which need to undergo splicing to remove the introns and re-splicing to join the exons ..after this process the resulting mRNA is a mature mRNA.
What is self splicing?
Intron that itself is the source of the enzymatic activity necessary for it removal. Splicing mechanism of pre-mRNA involving group I introns.
How is RNA altered after it is transcribed?
poly-A tail 7-methylguanine cap introns being removed (splicing)
Do mitochondria have introns?
No, prokaryotes do not have introns, and therefore do not do RNA processing. However, eukaryotes do.
Does splicing occur naturally?
Yes, it only occurs in eukartoyic mRNA as they only have the non coding region (introns)
How is excision to make the completed mRNA accomplished?
post transcriptional modifications such as cutting and splicing of exons!
What are the introns and exons?
An intron is a DNA region within a gene that is not translated into protein. After intron splicing (ie. removal), the mRNA consists only of exon derived sequences, which are translated into a protein.
What are the benefits to having introns?
The exact function of intron is yet unknown and they are usually considered junk segments of DNA. However, it has been observed that removal of introns from the native DNA sequence and then allowing its transcription does not facilitate the proper transcription of the region. As a first approximation, it is possible to view introns as unimportant sequences whose only function is to be removed from an unspliced precursor RNA in order to generate the functional mRNA, rRNA or tRNA product. However, recent studies show that this perspective is, in many cases, overly simplistic. It is now well-established that some introns themselves encode specific proteins or can be further processed after splicing to generate noncoding RNA molecules. Alternative splicing is widely used to generate multiple proteins from a single gene. Furthermore, some introns represent mobile genetic elements and may be regarded as examples of selfish DNA.
