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There are several different mutations that can cause hemophilia and there is no typical answer to this question. There are different segments of code on the X chromosome that is responsible for enabling production of Factors VIII & IX. A mutation anywhere within these areas can be responsible for hemophilia. The type of mutation as well as the location of the mutation in that code can influence the severity of hemophilia as well.
Lets look at a reversal mutation that results in the creation of a stop codon (this type of mutation is often called a nonsense mutation) early on in the code sequence. The stop codon tells the machinery to stop production of the factor protein molecule at that point. In this case, the molecule would never actually be made.
If we look instead at a point mutation resulting in simply an incorrect amino acid in that location (often called a missense mutation) half way through the code sequence, results can vary dramatically. The factor molecule will be made incorrectly, either not functioning for its purpose at all or simply doing a less than efficient job.
I hope that helps some.
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∙ 12y ago
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How does DNA or chromosomes cause hemophilia?
The "X" chromosome . . . I believe it is number 23 . . .
DNA replication results in two identical DNA molecules. What role do DNA helicases have in DNA replication?
DNA helicases break the hydrogen bonds in the DNA molecule
What happens during the S phrase?
During the S stage DNA synthesis occurs. (copying of the DNA)
How many copies of a DNA molecule results from two replications of a single DNA molecule?
Four.
What happens when there is a letter change in DNA?
what happen when dna letters are changed
A hereditary bleeding disorder that results from lack of clotting factors?
Hemophilia, Sickle Cell anemia.
Hemophilia results from an allele then is?
Recessive?? (i.e., you would need to inherit one from each parent to have hemophilia)
The disease that results from a failure to form blood clotting factor VIII is?
Hemophilia i think... but i could be wrong
What happens if hemophilia b gets diagnosed as hemophilia a?
it will become more superstitious or it will become powerful.
A genetic disorder that results from a defective protein in the clotting pathway?
hemophilia
How does DNA or chromosomes cause hemophilia?
The "X" chromosome . . . I believe it is number 23 . . .
If you have DNA results for the guy and the child can you use those results to determine if he is the father?
If you also have the mother's DNA, then yes.
What can cause EIA to give inaccurate results?
Pregnancy and hemophilia are two main reasons that these tests are inaccurate.
What happens to kids who don't get enough vitamin K?
The are sujects to hemophilia, hemoraggies and other diseases.
Is hemophilia a sex-limited or a sex-influenced trait?
Hemophilia, along with color blindness, is a sex-linked recessive trait. Hemophilia is when a person lacks a clotting factor in the blood. This results in the decreased ability to have blood clots. This can be dangerous because a person may internally or externally bleed to death. People with hemophilia must take clotting factors (by needle injection) frequently throughout their lives in order to live. As it is to be known, mothers are the carriers of these kind of traits. If a mother has the hemophilia trait, that means that her son will have hemophilia.
DNA replication results in two identical DNA molecules. What role do DNA helicases have in DNA replication?
DNA helicases break the hydrogen bonds in the DNA molecule
What happens during the S phrase?
During the S stage DNA synthesis occurs. (copying of the DNA)
