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If tissue lymphatics are blocked by a tumor or lymph nodes were excised to stop a tumor from metastasizing, the obstruction causes reduced lymphatic drainage, which leads to increased interstitial hydrostatic pressure, interstitial fluid volume, and eventually edema.
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What are the results when the lymphatics are blocked due to tumors?
The fluid that the lymphatics are supposed to drain is at a stand still and it keeps accumulating without draining. The area if an extemity becomes useless and like a large stump.
Is lymphedema an autoimmune disease?
No it is not an auto immune disease. It can be congenital due to poorly developed lymphatics, or it can be due to blocked or damaged lymphatics. One of the most common causes in India and Africa is Filariasis which causes blocked lymphatics, and can be treated with medication. It can also be seen in pelvic tumours, when the swelling causes pressure on the vessels and lymphatics. It is seen most commonly now after radical surgery when the lymph nodes are removed for malignant disease.
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Throat cancer refers to cancerous tumors that develop in your throat (pharynx), voice box (larynx) or tonsils. Cancerous tumors typically develop at the cellular level due to mutagens and carcinogens, causing mutations in DNA sequences that code for proteins that limit and monitor mitosis. This mutation leads to the lack of those proteins, causing uncontrollable mitotic divisions leading to the development of tumors.
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Are pituitary tumors noncancerous and cause any symptoms?
Many pituitary tumors are, in fact, noncancerous. They do, however, cause some symptoms due to pressure on the area. Some are listed as nasal drainage, nausea, droopy eyelids and even some vision loss. If you are concerned about the possibility of such tumors, then please seek medical advice.
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