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The best way to travel from Nashville Tennessee to Knoxville Tennessee is by Interstate 40.
765 miles
Highway 401 in Toronto, Ontario, Canada
There are many roads that head south out of Nashville. Popular highways include highway 65, 41, 24, and highway 155.
Nashville Tenn., Highway 431 North
Take AUTOROUTE 20 OUEST to Ontario where it becomes HIGHWAY 401 WEST.Continue on HIGHWAY 401 WEST to Toronto.
Detroit is about 4 hours from Toronto and Buffalo is about 2 hours from Toronto.
Highway 40 connects Nashville and Knoxville to the Smokey Mountains.
It should take 12 hours to drive from Toronto to Nashville. Keep in mind that the time zone is different so it'll probably only take you 11.
Take the 401 highway east from Toronto, past Oshawa, take the 115 highway north-east to Peterborough. It's about 90 minutes.
108 km taking HIGHWAY 401, HIGHWAY 8, and HIGHWAY 85.
take the transcanada highway