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An acetylgalactosamine is the N-acetyl derivative of galactosamine which is a repeat unit in glycosaminoglycans.
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What are the 4 monosaccharides?
There's five; glucose, fructose, galactose, xylose and ribose.
What is the role of Glycoproteins and glycolipids?
Glycoproteins are the proteins covalently attached to carbohydrates such as glucose, galactose, lactose, fructose, sialic acid, N-acetylglucosamine, N-acetylgalactosamine, etc. Glycolipids are carbohydrate-attached lipids. Their role is to provide energy and also serve as markers for cellular recognition.The antigens which determine blood types belong to glycoproteins and glycolipids
What diferrenciates blood group O from other blood groups?
Type O red cells do not contain the terminal sugars on the RBC membranes that distinguish type A (N-acetylgalactosamine), type B (galactose) or type AB (both). Additionally, the plasma of a type O individual contains naturally occurring anti-A, anti-B and anti-AB antibodies (unique to type O individuals) that are directed against non-self RBC ABO antigens.
Type blood A has what characteristics?
Blood group A individuals will have Anti-B antibodies. Group A individuals make up 28% of the Asian population, 27% of the Black population, and 40% of the White population. The genes for group A are on chromosone 9, and the gene product is N-Acetylgalactosaminyltransferase, which transfers N-Acetylgalactosamine to an oligosaccharide chain on the surface of the red blood cell. 80% of group A people have both branched and linear oligosaccharide chains. 20% of group A people are a subgroup called A2, and the oligosaccharide chains are linear only. It is possible for an A2 individual to make Anti-A antibodies. Several other rare sub-groups of A also exist. Source: Basic & Applied Concepts of Immunohematology, Second Edition, by Kathy D Blaney and Paula r. Howard.
What is proteoglycans composed of?
A proteoglycan is a protein + glycosaminoglycan a GAG >20 porteoglycans genes So then you have GAG which are the Glycosaminglycan attach to the core protein. This core protein. The repeating core. This means they have glucuronic acid, or iduronic acid with the OOC attached to the sugar. With N-acetylgalactosamine-4-sulphate and they have the SO3 negative charge on them and this makes water/contains water. They are attached to serine on the protein core. Hyalurnan is not made in the same way. and is secreted in the wounds and other things. Aggrecan aggregate has a hyaluronin molecule which is not created in the same way and attaches these proteins and they have keratin and chondronin sulphate. Perican along with the basement membrane, act as a sieve for for the incoming molecules. They mainly have 4 Functions which you need to basically remember They hydrate space for the negative charges. Selective sieves for regulation of molucules trafficing. Major role in chemical signalling between the cells (growth factor signalling, FGF) So basic signaling. And they bind proteisase.
What galactocemia is worse type 1 2 or 3?
classic| severe. classic galactosemia, can result in life-threatening complication's (classic galactocemia is the most severe type of this disorder)clinical virant| moderate?biochemical virant| mild/moderate?durate virant| mild/severe?
