Rueful, remorseful.
Forlorn
Leukemia is something sad that starts with "l".
abuse
Another word for "sad" in Spanish is "triste."
jobless
tragedy
elegy
bullying
Somber
Some sad words:awfulbadcrushingdreadfulennuifriendlessglumhopelessilljoylessnessknocked downlethargymoodyneedyoverwhelmedpeevishqueasyremorsefulsorrytroubleduneasyvulnerablewoefulx...yearningzealless
sad
Another word for devastating is sad