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What is base pair affinity?

Updated: 12/14/2022
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11y ago

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It refers to the binding preferences between the nucleotides.

Adenine has an affinity for base pairing with thymine, while guanine base pairs with cytosine.

Uracil base pairs with adenine in Rna.

This ' base pair' bonding is actually based upon the weaker yet no less bio-specific Hydrogen Bonding system. One nucleotide base pair shares two Hydrogen bonds while the other nucleotide base pair shares three Hydrogen bonds: hence the slight changes in shapes that guarantee absolute specificity of replication and transcription.

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11y ago
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