From the information provided, it sounds like you're dangerously low on oil.
Driving at 50mph or above what causes a loud knocking clicking sound during acceleration?
The knocking noise could be one of several things. The wheel bearing, a worn steering or suspension part, or road debris could be causing the noise.
your foot
it could be a exhaust leak.
you could have a wire broke in the tire
Need car's weight and stopping power to compute.
no parking/stopping
The brakes are the primary cause of stopping a car whilst driving.
Driving, turning, and stopping. Thats about it.
No.
check CV joints
As a general rule of thumb, no.